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Implementations have found ways to optimize transform pipelines by collapsing identity transforms, short-circuiting non-observable paths, deferring buffer allocation, or falling back to native code that does not run JavaScript at all. Deno, Bun, and Cloudflare Workers have all successfully implemented "native path" optimizations that can help eliminate much of the overhead, and Vercel's recent fast-webstreams research is working on similar optimizations for Node.js. But the optimizations themselves add significant complexity and still can't fully escape the inherently push-oriented model that TransformStream uses.
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帝國理工學院醫療NHS信託（Imperial College Healthcare NHS Trust）的顧問婦科醫生理查德・史密斯教授（Prof Richard Smith）25年前就開始研究子宮移植，並親自見證了雨果的誕生。他表示，「一支龐大的團隊」參與了整個過程——從移植手術、胚胎移植到分娩本身。